Asian Journal of Pharmacy and Technology

Shashikant Chandrakar ¹, Amit Roy ¹, Ananta Choudhury ¹, Suman Saha ¹, Sanjib Bahadur ¹, Pushpa Prasad ¹

Affiliations
1 Columbia Institute of Pharmacy, Raipur, (C.G.), 493111, IN

Abstract

Eye drops are the most acceptable dosage form by ocular route, which as has disadvantage of bioavailability. The anatomical and physiological constrains limited permeability of drug such as drug loss from the ocular surface by lachrymal drainage, blood-ocular barriers. A number of drug delivery system has been developed to improve the bioavailability and to prolong the residence time of drugs on the eye. Such as promising system for ocular drug delivery is a microemulsion. Microemulsions are clear, stable, isotropic mixtures of oil, water and surfactant, frequently in combination with a cosurfactant. This review gives an overview of the potential of microemulsions as delivery vehicles for eye. Both lipophilic and hydrophilic characteristics are present in microemulsions, so that the loaded drugs can diffuse passively as well get significantly partitioned in the variable lipophilic-hydrophilic corneal barrier.

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Amit Roy ¹, Pushpa Prasad ¹, Nirmala Gupta ²

Affiliations
1 Columbia Institute of Pharmacy, Raipur, IN
2 Institute for Excellence in Higher Education (IEHE), Bhopal, IN

Abstract

Medicinal mycology has deep and firm ischolar_mains in fungi traditional uses in the medicine of far east. Medicinal mushrooms are moving from fringe to mainstream use with a greater number of people seeking remedies and health approaches free from side effects caused by synthetic chemicals. There are about 38,000 different varieties of mushrooms in which 300 mushroom species are edible and pharmacological research is going on for its medicinal properties. This article aims to provide a comprehensive review on the edible and medicinal properties of Volvariella volvacea. Volvariella volvacea is an edible mushroom belonging to Pluteaceae family and is widely grown in tropical, subtropical regions and temperate regions of both the eastern and the western hemispheres. It is widely used in traditional medicinal system of India and is reported to possess anti-tumor, immunosuppressant and immunomodulatory effects. It is known as a rich source of protein, fibers (chitin), vitamins (large amount of vitamin C, and also all water soluble vitamins like riboflavin, biotin and thiamine), fats (5.7%), carbohydrates (56.8%), amino acids (all essential amino acids like alanine, arginine, glycine, serine etc.), unsaturated fatty acids, essential minerals (potassium, sodium and phosphorus) and has low calorific values. The innumerable medicinal properties of V. volvacea as well its phytochemical investigations prove its importance as a valuable medicinal mushroom.

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Amit Roy ¹, Pushpa Prasad ¹

Affiliations
1 Columbia Institute of Pharmacy, Raipur, (Chhattisgarh), IN

Abstract

A mushroom is the fleshy, spore-bearing fruiting bodies of fungi typically produced above ground on soil or on their food sources. Calocybe indica is rich in protein, lipid, fiber, carbohydrate and vitamin and incorporates an ample amount of essential amino acid and low fat product. History displayed that C. indica used as the food supplement around the world for a long time because it is rich source of thiamine, riboflavin, nicotinic acid, pyridoxine, biotin, and ascorbic acid. C. indica is used in the treatment of various diseases and disorders, as reported in scientific literature. It has become the third commercially grown mushroom in India after button and oyster mushrooms. Currently, the people of India are showing less interest in cultivation of this mushroom due to its low productivity. The researchers developed new techniques to improve the production of C. indica and now it is required to bring awareness in people about these techniques. The purpose of the present review is, to sum up, the available data and to reproduce the current status of this mushroom in research area.

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